Job Description
Acknowledgement of CountryCSIRO acknowledges the Traditional Owners of the land, sea and waters, of the area that we live and work on across Australia. We acknowledge their continuing connection to their culture and pay our respects to their Elders past and present.Child safetyCSIRO is committed to the safety and wellbeing of all children and young people involved in our activities and programs. View our .The opportunityBe part of the award-winning CSIRO Molecular Diagnostics Solutions teamWork alongside molecular biologists, bioinformaticians, statisticians and cliniciansGreat opportunity if you have a PhD in molecular biology, (epi)genetics, bioinformatics or a related disciplineCSIRO Early Research Career (CERC) Postdoctoral Fellowships provide opportunities to scientists and engineers who have completed their doctorate and have less than three years of relevant postdoctoral work experience. These fellowships aim to develop the next generation of future leaders of the innovation system.The CERC Fellow will be part of the Integrated Diagnostics team, to undertake the development of a novel liquid biopsy assay and build software for real-time data analysis. The team is currently developing novel diagnostic approaches and ex vivo technologies for cancer, metabolic disease, Alzheimer's disease, and acute trauma. The Integrated Diagnostics team has previous translation success, including the co-development of the Colvera™ and Colostat™ blood tests with our commercial partners.Across this CERC Fellowship you will work on the development of a blood test useful for diagnosing tissue/organ damage. This cutting-edge precision medicine technology makes use of DNA sequencing to inspect DNA fragments in the bloodstream released from dying cells.The CERC Fellow will be part of a project team consisting of molecular biologists, bioinformaticians, statisticians, and clinicians. Your role will be to lead the development of the liquid biopsy assay. This will involve the establishment of optimal lab processes for sequencing cell-free DNA, the creation of a bioinformatics pipeline to process streaming data, and the development of software for a web browser-based user interface.Your duties will include:Utilising molecular biology and bioinformatics skills for biomarker and classifier development for a liquid biopsy test.Engaging with clinical collaborators to understand unmet diagnostic needs and exemplifying the classification method in several proof-of principle clinical areas.Working with the project team to architect and build software for processing sequencing data in real-time.Carrying out innovative, impactful research of strategic importance to CSIRO that will, where possible, lead to novel and important scientific outcomes.Location: Westmead, Sydney, NSWSalary: AU$96k - AU$105k plus up to 15.4% superannuationTenure: Specified term of 3 yearsReference: 97269To be considered you will need:A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area, such as molecular biology, (epi)genetics or bioinformatics. Please note: To be eligible for this role you must have no more than 3 years (full-time equivalent) of postdoctoral research experience.Demonstrated understanding of molecular biology, genomics, and associated laboratory methods. Highly proficient in the generation and quality assessment of second and/or third generation sequencing libraries.Demonstrated proficiency in at least one programming language for statistical computing (R or Python preferred).Demonstrated knowledge and experience in bioinformatics for the analysis and interpretation of genomics datasets.High level written and oral communication skills with the ability to represent the research team effectively internally and externally, including the presentation of research outcomes at national and international conferences.For full details about this role please view theEligibilityApplications for this position are open to Australian/New Zealand Citizens, Australian Permanent Residents and Australian temporary residents currently residing in Australia. Appointment to this role is subject to provision of a national police check and may be subject to other security/medical/character requirements.The successful candidate will need to be able to commence by 30 November 2024.Flexible working arrangementsWe work flexibly at CSIRO, offering a range of options for how, when and where you work.Diversity and inclusionWe are working hard to recruit people representing the diversity across our society, and ensure that all our people feel supported to do their best work and feel empowered to let their ideas flourish.About CSIROAt CSIRO Australia's national science agency, we solve the greatest challenges through innovative science and technology. We put the safety and wellbeing of our people above all else and earn trust everywhere because we only deal in facts. We collaborate widely and generously and deliver solutions with real impact.CSIRO is committed to values-based leadership to inspire performance and unlock the potential of our people.Join us and start creating tomorrow today!How to applyPlease apply on-line and provide a cover letter and CV that best demonstrate your motivation and ability to meet the requirements of this role.Applications close18 August 2024, 11:00pm AESTCSIRO
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