Job Description
About ANGLE:
ANGLE is a world leading liquid biopsy company with sample-to-answer solutions.
ANGLE's proven patent protected circulating tumor cell (CTC) harvesting technology is known as the Parsortix® system. ANGLE's Parsortix® system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood.
The Parsortix system enables a liquid biopsy (a simple blood test) to be used to provide the circulating metastatic breast cancer cells to the user in a format suitable for multiple types of downstream analyses. The system is based on a microfluidic device that captures cells based on a combination of their size and compressibility. The system is epitope independent and can capture all phenotypes of CTCs (epithelial, mesenchymal and EMTing CTCs) as well as CTC clusters in a viable form (alive). CTCs harvested from the system enable a complete picture of a cancer to be seen; as being an intact cell they allow DNA, RNA and protein analysis as well as cytological and morphological examination and may provide comparable analysis to a tissue biopsy in metastatic breast cancer. Because CTC analysis is a non-invasive process, unlike tissue biopsy, it can be repeated as often as needed. This is important because cancer develops and changes over time and there is a clear medical need for up-to-date information on the status of a patient's tumor. In addition, the live CTCs harvested by the Parsortix system can be cultured, which offers the potential for testing tumor response to drugs outside the patient.
Join our Team:
This is an exciting time at ANGLE and our Research and Development team in Guildford are looking for a Cell Culture Technician specialising in maintaining the Cell Culture platform in accordance with the R&D group leader. This important position, will undertake work that requires the Cell Culture Technician to primarily be responsible for the smooth running of cell culture facility according to standard operating procedures, providing technical support to the scientific team. The job is laboratory based, working in a multi-disciplinary team.
This position provides invaluable lab experience and teamwork skills, and the opportunity to learn about and contribute to product development in an industry environment. This is a scientific support role and will involve routine tasks.
At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We offer the potential for significant corporate growth and career development. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.
We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.
Principal Accountabilities:
- Responsible for maintaining the cell culture platform in accordance with the R&D group leader.
- Responsible for maintaining day to day running of the cell culture facility, including: maintaining mammalian cell lines culture and cell culture facility consumables, receiving and unpacking deliveries and preparing buffers and culture media.
- Generating labelled cells for general laboratory use.
- Preparing cells for routine testing of mycoplasma infection and cell authentication.
- Keeping the cell culture facility clean, tidy and minimising contamination risks at all times.
- Responsible for maintaining excellent cell culture documentation as appropriate within the quality system. Ensuring regulatory compliance of all work undertaken by themselves and any other work carried out in the cell culture facility.
- Undertake additional ad-hoc tasks as required.
Qualifications, Experience, Knowledge and Attributes:
- B.Sc. or equivalent in Life Sciences or A Levels and have relevant laboratory experience;
- Excellent aseptic technique and extensive relevant technical knowledge is required.
- A strong understanding of the importance of accurate record keeping within a strictly controlled quality system is essential.
- Experience in a full-time cell culture role combined with use of cell culture equipment would be a plus;
- Experience of working to strict quality standards such as ISO9001, preferably ISO13485 would be an advantage.
- An eye for detail and commitment to high quality data.
- A flexible, can-do approach to the requirements of the job.
- Strong team player.
- Strong verbal and written communication skills.
- Ability to multitask and prioritise to meet deadlines.
- Ability to work both independently with minimal supervision as well as in a team environment.
- An eye for detail and commitment to high quality data.
- Continuous learner with a keen appetite for cross-disciplinary work.
- Entrepreneurial thinking and work ethic.
As a member of our highly skilled and fast-growing team you will receive opportunities for development and a competitive benefits package.
Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.
Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.
Important notice to Employment Businesses/ Agencies:
ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Job Type: Full-time
Schedule:
Work Location: One location
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